Reconstitution of the tubular endoplasmic reticulum network with purified components
نویسندگان
چکیده
منابع مشابه
Protein translocation into proteoliposomes reconstituted from purified components of the endoplasmic reticulum membrane.
We have reproduced the process of protein transport across and of protein integration into the mammalian endoplasmic reticulum membrane by the use of proteoliposomes reconstituted from pure phospholipids and purified membrane proteins. The transport of some proteins requires only two membrane protein complexes: the signal recognition particle receptor, needed for targeting of a nascent chain to...
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ژورنال
عنوان ژورنال: Nature
سال: 2017
ISSN: 0028-0836,1476-4687
DOI: 10.1038/nature21387